Home / Sterile BFS CDMO | Blow-Fill-Seal Contract Manufacturing Services /
Blow-Fill-Seal (BFS) technology is the gold standard for aseptic filling of sterile liquid products — combining container formation, sterile filling, and sealing in a single automated step. Whether you´re manufacturing ophthalmics, respiratory treatments, or injectable solutions, a reliable sterile BFS CDMO ensures unmatched sterility, efficiency, and compliance.
With complete blow-fill-seal contract manufacturing capabilities, these CDMOs deliver scalable, GMP-compliant production of sterile single-dose and multi-dose containers for global markets.
Partnering with an experienced BFS CDMO for sterile drugs offers:
Integrated container formation and aseptic filling in ISO 5 conditions
Minimal human intervention, reducing contamination risk
Compatibility with unit-dose, multi-dose, and twist-off formats
Support for ophthalmic, nasal, oral, injectable, and respiratory therapies
Preservative-free system options
Regulatory readiness (FDA, EMA, WHO PQ, etc.)
Scalability from clinical to high-volume commercial batches
BFS is especially well-suited for sterile products where safety, speed, and format flexibility are essential.
Leading blow-fill-seal contract manufacturing companies typically offer:
Formulation development for low-viscosity sterile liquids
Container design and customization (LDPE, PP)
Sterile BFS filling for volumes from 0.2 mL to 100 mL+
Single-dose and multi-dose formats with tamper-evident designs
Microbiological and particulate control testing
Cold chain management, if required
Labeling, secondary packaging, and serialization
Regulatory support for ANDA, NDA, and EU submissions
These services support BFS products for ophthalmology, ENT, pulmonology, wound care, and more.
Collaborating with a qualified BFS CDMO offers key benefits:
Superior sterility assurance with closed-system processing
Lower production costs due to high-speed automation
Ideal for preservative-free products, especially for pediatric or ophthalmic use
Reduced packaging waste and improved dosing accuracy
Fast time to market with integrated fill-finish and packaging solutions
BFS is the solution of choice for high-volume, patient-friendly sterile liquids.
Some of the most trusted sterile BFS CDMO providers include:
Pharmaloop (a Salvat company): Fully integrated CDMO solutions for Blow-Fill-Seal (BFS), sterile multidose, non-sterile multi-dose, sachets, capsules and tablets. [See CDMO profile]
Steriles CDMO Companies | Steriles Contract Manufacturing Services
FDF CDMO Services | Finished Dosage Forms Contract Manufacturing
At MAI CDMO, we connect pharma and biotech companies with the most experienced steriles BFS CDMO providers offering turnkey blow-fill-seal contract manufacturing. Whether you’re scaling a preservative-free therapy, launching a hospital-use product, or exploring unit-dose innovation, we’ll help you find a partner ready to deliver quality and compliance.
Ready to advance your sterile product with BFS technology? Contact us today and find your ideal CDMO partner.
If you have any questions or suggestions, click here. We will be happy to assist you.