Pharmaceutical pellets — also known as multiparticulates — are widely used for controlled-release, taste-masked, and combination oral dosage forms. Whether delivered in capsules, sachets, or as layered tablets, pellets require precise process control, functional coating expertise, and scalable GMP infrastructure. That’s why leading brands rely on specialized pellets CDMO companies for development and production.
With integrated pellets contract manufacturing services, these CDMOs support end-to-end development, from drug layering and spheronization to coating, encapsulation, and packaging.
How to Choose Pellets CDMO Companies
When evaluating pellets CDMO companies, consider:
- Expertise in pelletization techniques: extrusion-spheronization, layering, or prilling
- Controlled-release coating capabilities: enteric, sustained, delayed-release
- Experience with functional excipients and polymers (e.g., Eudragit®, HPMC)
- Particle size distribution control and uniformity testing
- Batch scalability for clinical, pilot, and commercial volumes
- Capsule or sachet filling options for pellet-based delivery
- GMP compliance and regulatory inspection readiness
The ideal CDMO ensures formulation performance, dose accuracy, and patient compliance — especially for modified-release products.
Key Services Offered by Pellets Contract Manufacturing Partners
Top-tier pellets contract manufacturing providers offer:
- Formulation development for IR, SR, ER, DR, or pulsatile release
- Drug layering onto inert cores or APIs
- Extrusion and spheronization for uniform pellet production
- Functional coating with polymers for targeted release
- Blending and encapsulation into hard gelatin or HPMC capsules
- Sachet or stick pack filling for oral granular delivery
- In vitro dissolution testing and release profile validation
- Stability testing and regulatory documentation
These services enable versatile, patient-friendly oral delivery systems that offer superior therapeutic performance.
Advantages of Partnering with Pellets CDMO Companies
Collaborating with experienced pellets CDMO companies offers important benefits:
- Improved bioavailability through targeted release profiles
- Enhanced patient compliance with taste masking and dose flexibility
- Reduced GI side effects via delayed or sustained delivery
- Fixed-dose combination support through multiparticulate blends
- Flexible fill formats in capsules, sachets, or tablets
Pellet-based formulations are increasingly favored for complex oral therapies — and your CDMO partner should support that innovation.
Pellets CDMO Companies
Some of the most trusted pellets CDMO companies include:
- Lannett: Oral Solid Dose (OSD) and Liquids. [See CDMO profile]
- Pharmaloop (a Salvat company): Fully integrated CDMO solutions for Blow-Fill-Seal (BFS), sterile multidose, non-sterile multi-dose, sachets, capsules, pellets, and tablets. [See CDMO profile]
- Cenexi: Injectables manufacturing. [See CDMO profile]
- Aenova: Competence Center for complex conventional solids, including pellets. [See CDMO profile]
- Sichuan Huiyu Pharmaceuticals Co., Ltd.: Development and production of complex and high-value dosage forms: implants, oral solids (OSD) and sterile forms. [See CDMO profile]
- I+Med: Developer and manufacturer of new drug products using controlled release technologies: implants, oral liquids and semisolids, and oral solids. [See CDMO profile]
- Adragos Pharma: Specialist in the development of Value Added Medicines, manufacturing oral liquids and semisolids, as well as oral solids (OSD). [See CDMO profile]
- Sidefarma: Specialized in the manufacture of small and medium-size batches for pharmaceutical companies: oral liquids and semisolids, and oral solids (OSD). [See CDMO profile]
- Skyepharma: Fully integrated FDF CDMO, Skyepharma is a key player in drug development and delivery of oral technologies serving the global pharmaceutical, biotech and consumer health industries. [See CDMO profile]
- FAES FARMA | DERIO facility: Developer and manufacturer of human medicinal products, offering comprehensive pharmaceutical development and manufacturing capabilities. [See CDMO profile]
- Glatt Pharmaceutical Services GmbH Co. & KG: cGMP-compliant CDMO providing end-to-end services for complex oral solid dosage forms, from development through commercial manufacturing. [See CDMO profile]
- Adare Pharma: CDMO delivering turnkey product development and commercial manufacturing expertise focused on oral dosage forms for the pharmaceutical, animal health, and OTC markets. [See CDMO profile]
- Seda Pharma Development Services: Specialized CDMO offering integrated pharmaceutical development and clinical pharmacology services to enable efficient development of optimal medicinal products, from conventional to complex formulations. [See CDMO profile]
Related Information
Let MAI CDMO Help You Find the Right Pellets CDMO Partner
At MAI CDMO, we help pharmaceutical and nutraceutical innovators connect with world-class pellets CDMO companies offering full-spectrum pellets contract manufacturing services. Whether you’re developing a once-daily extended-release product or a taste-masked pediatric formulation, we’ll match you with the right partner for performance, compliance, and speed to market.
Need expertise in multiparticulate formulation and pellet production? Contact us today to find your ideal CDMO partner.
