Commercial API Small Molecules Synthesis

The Pharmaron Cramlington site, located in Northumberland, UK, was acquired by Pharmaron in 2022, significantly enhancing the company’s technologies and capabilities.
Cramlington is an FDA-, EMA-, MHRA-, and PMDA-approved facility, equipped with reactors ranging from 50 L to 10,000 L. It supports batch sizes from just a few grams to several hundred kilograms, covering the full spectrum from clinical development to commercial manufacturing.
The site comprises two kilo labs, a pilot plant (250 L to 1,000 L), and two commercial-scale buildings (3,000 L to 10,000 L), offering a total reactor capacity of 170,000 L.
Fully integrated into the Pharmaron global network, the Cramlington site is backed by a team of 250 process chemists based in the UK. It also plays a key role in Pharmaron’s successful hybrid model between China and the UK: advanced intermediates are produced in China, shipped to Cramlington, and converted into final APIs in the UK.This model ensures a robust, flexible supply chain while maintaining cost-efficiency (COGs).