CZ Vaccines | CZ Vaccines | Large Scale Plant Portugal

Manufacturing

Upstream

Culture process in flasks

Biological security chamber

Stainless-steel bioreactors:

• 1 x 100 L
• 1 x 300 L
• 2 x 2500 L

Media preparation

Stainless-steel bioreactors:

• 1 x 300 L
• 1 x 800 L
• 2 x 3000 L

Downstream and purification

Our facilities are prepared to receive and install any kind of equipment.

Currently, the Downstream area has 6 stainless-steel bioreactors, a room prepared for chromatography and purification processes, and two +4°C chambers.

Fill & Finish

1 filling line: IMA machine

• Vial washing machine
• Filling machine loading
• Capacity for 2R vials: 24,000 vials/hour
• Possibility of adding other vial sizes
• Final washing machine

1 lyophilizer: IMA machine (capacity to add another lyophilizer)

• Automatic lyophilizer with capacity of up to 180,000 vials per run

Storage: (+2 - +8°C), (-20°C) and (-80°C)

2 double-door autoclaves connecting the washing and depyrogenation tunnels with each filling room