Adragos Pharma | Adragos Pharma | Maisons-Alfort

With over 77 years of specialization in sterile drug manufacturing, the Maisons-Alfort facility is a global hub for prefilled syringes (PFS), liquid and lyophilised vials, featuring high-speed aseptic filling, large-scale freeze-drying, and advanced inspection systems. It operates under stringent GMP standards with CIP/SIP and RABS technologies.

 

Pre-Filled Syringes (PFS)

Technology

Two filling lines with RABS technology.

3 types of PFS:

• Standard
• Preventis
• Eris

Capacity

• Maximum Capacity: up to 540 syringes/min.
• 150 million units per year.
• Format: 0,5 mL and 1 mL.

Inspection

• 2 Seidenader lines 100% automated.
• Max capacity: up to 600 syringes/min.

Packaging

• 5 thermoforming packaging lines.
• 1 packaging plastic-free line.
• Speed: up to 360 syringes/min.
• Kit formats: 2- to 76-syringe packs, including Blister-to-Box (BIB) options.

 

Vials Liquid & Lyo

Technology:

• 1 filling line with RABS technology
• 2 large automated loading/unloading freeze dryers

Capacity

• Maximum Capacity: up to 6 million vials
• Filling: up to 300 vials/min
• Freeze-drying: up to 70,000 vials
• Crimping: up to 350 vials/min
• Format: 6R, 10R, 7 mL, 10 mL, 15 mL, 22 mL

Inspection

• Semi-automated inspection
• Max capacity: up to 100 vials/min

 

Packaging

• 1 plastic-free packaging line for vials with solvent ampoules
• 1 blister line for combinated vial kits with BIB options
• Cartooning box: up to 130 vials/min
• Thermoforming machine: up to 75 blisters/min for combined kits

Large storage capacity through internal and external warehouse models to ensure continuity of supply and scale-up flexibility, with GMP-qualified warehouse processes, temperature mapping, and continuous temperature monitoring.