FDF / DRUG PRODUCTS CHEMICAL-SYNTHETIC SERVICES in
Specialized contract research solutions designed to accelerate your drug discovery and development programs with precision and expertise.
About the plant
Our Capabilities: Precision and Innovation in Chemistry
At Aventaa, we pride ourselves on tackling complex chemical challenges with precision and innovative solutions.
Exceptional Team Expertise
Our team is the cornerstone of our success, comprising highly versatile researchers with deep specialization in diverse chemical areas:
Our onboard expert and team lead, possesses crucial knowledge in chemistry and is internationally recognized for troubleshooting complex reactions.
Chiral Chemistry: Expertise in developing and separating chiral mixtures.
Complex Moiety Synthesis: Proficient in synthesizing challenging structures such as beta-lactams, mycin groups, and peptides.
Rare Nitroso Products: A proven track record in achieving rare nitroso products (e.g., Vilanterol, Plerixafor impurities) and generating nitroso from various amines.
Stable Isotopes & Analogues: Capable of forming stable isotopes and developing analogous compounds crucial for drug development.
Advanced Technical Capabilities
Our laboratory is equipped to handle a broad spectrum of synthetic projects efficiently:
High-Throughput Synthesis: Ability to perform 40 reactions simultaneously with advanced overhead stirring and heating facilities.
Sustainable Process Development: Committed to developing processes that are not only efficient but also environmentally conscious.
Specialized Reactions: Expertise in performing rare and complicated coupling reactions.
State-of-the-Art Infrastructure
Our modern facility is designed for optimal performance, ensuring speed, purity, and precision in every project.
Laboratory & Workflow
Comprehensive Purification: Equipped with advanced purification systems including Flash Chromatography and Preparative HPLC for faster isolation of pure compounds. We also maintain core competency in meticulous manual column purification.
Analytical Prowess: In-house LC-MS and Mass Spectrometry for immediate and accurate identification of different molecules.
Extensive Characterization Support: Collaborative access to advanced analytical techniques such as NMR, Chiral HPLC, TGA, ROI, CHNS, UV, and IR to ensure thorough characterization and data integrity.
Optimized Workspace: Nine highly efficient fume hoods ensure a safe and fast synthesis environment, complemented by standardized evaporating instruments for streamlined workflows.
Secure Storage: Dedicated and compliant storage facilities for volatile and hazardous chemicals.
Standards and Digital Integration
Modern ELN Software: Our dedicated IT team manages a state-of-the-art Electronic Lab Notebook (ELN) system for precise tracking and documentation of all experiments.
Advanced Software Tools: Utilization of industry-leading software like ChemDraw and literature databases such as Scifinder ensures comprehensive research and intelligent synthetic design.
Unwavering Commitment to Safety
The safety of our valuable scientific team and our operational environment is our paramount concern.
Robust Safety Protocols: We adhere to very strong Standard Operating Procedures (SOPs) and a defined workflow to prevent any accidents or near misses.
Comprehensive Training: Our training team conducts weekly seminars and mock drills to ensure continuous awareness and readiness in safety and infrastructure protection.
Exposure Control: We utilize efficient fume hoods and rotavapor fume absorbing systems to minimize chemical exposure for our team.
Proactive Incident Management: A dedicated committee brain-storms and troubleshoots any near-miss or accident, fostering a culture of continuous improvement.
Certifications
- ISO
Activity
- FDF / DRUG PRODUCTS, CHEMICAL-SYNTHETIC, SERVICES, Intermediates, Fine Chemicals, API (Active Pharmaceutical Ingredients) manufacturing
Features
- Uses: N/A
- Toxicity (OEB classification): N/A
- DEA: N/A
- BSL: N/A
- Therapeutic areas: N/A
- Markets: N/A
Batch Size / Reactor
- Small, Medium, 1 - 10 L
Services
- Development services, Manufacturing services, Analytical / QC services, R&D, Process development, Process optimization, Research batches, Pilot batches, Analytical methods development, Analytical methods validation, Release testing of raw materials, Release testing of product, Chiral resolution screening, Impurity synthesis
